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Article

Cystic fibrosis transmembrane conductance regulator gene mutations and glutathione S-transferase null genotypes in cystic fibrosis patients in Brazil.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Jan 2000

Lima Carmen Silvia Passos, Ortega Manoela Marques, Marson Fernando Augusto Lima, Zulli Roberto, Ribeiro Antônio Fernando, Bertuzzo Carmen Silvia

Abstract excerpt

OBJECTIVE: To determine the effects that mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene and deletion of the glutathione S-transferase (GST) genes mu-1 (GSTM1) and theta-1 (GSTT1) have on the clinical course of cystic fibrosis (CF) in patients residing in the southeastern region of Brazil. METHODS: The study sample consisted of all consecutive CF patients treated at the Hospital de...

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Identifiers

PMID: 22407040
DOI: 10.1590/s1806-37132012000100008

Genes

CFTR
GSTM1
GSTT1

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