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Article

Human versus porcine mesenchymal stromal cells: phenotype, differentiation potential, immunomodulation and cardiac improvement after transplantation.

Journal of cellular and molecular medicine - 1 Aug 2012

Noort W A, Oerlemans M I F J, Rozemuller H, Feyen D, Jaksani S, Stecher D, Naaijkens B, Martens A C, Bühring H J, Doevendans P A, Sluijter J P G

Abstract excerpt

Although mesenchymal stromal cells (MSCs) have been applied clinically to treat cardiac diseases, it is unclear how and to which extent transplanted MSCs exert their beneficial effects. To address these questions, pre-clinical MSC administrations are needed for which pigs appear to be the species of choice. This requires the use of porcine cells to prevent immune rejection. However, it is currently unknown to...

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Identifiers

PMID: 21973026
DOI: 10.1111/j.1582-4934.2011.01455.x
PMCID: PMC3822695

Genes

MSC
SLA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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