Article
Performance of PREMM(1,2,6), MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jul 2012
Mercado Rowena C, Hampel Heather, Kastrinos Fay, Steyerberg Ewout, Balmana Judith, Stoffel Elena, Cohn David E, Backes Floor J, Hopper John L, Jenkins Mark A, Lindor Noralane M, Casey Graham, Haile Robert, Madhavan Subha, de la Chapelle Albert, Syngal Sapna
Abstract excerpt
PURPOSE: Lynch syndrome accounts for 2-5% of endometrial cancer cases. Lynch syndrome prediction models have not been evaluated among endometrial cancer cases. METHODS: Area under the receiver operating curve (AUC), sensitivity and specificity of PREMM(1,2,6), MMRpredict, and MMRpro scores were a...
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