Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression, purification and antimicrobial activity of puroindoline A protein and its mutants.

Amino acids - 1 Oct 2012

Miao Yingjie, Chen Ling, Wang Cheng, Wang Yajuan, Zheng Qian, Gao Chunbao, Yang Guangxiao, He Guangyuan

Abstract excerpt

Wheat puroindoline proteins, PINA and PINB, play key roles in determining wheat grain hardness as well as in defending the plant against pathogens. PINA has much greater membrane-binding property and antimicrobial activity because it contains more tryptophan residues in the unique tryptophan-rich domain (TRD). In order to obtain proteins with higher antimicrobial activity, mutants of PINA containing two or three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular Dichroism
Share to Genetic Engineering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microbial Viability

Share to Protein Structure, Secondary

Share to Staphylococcus aureus

Share to Structure-Activity Relationship

Share to Triticum

Share to Tryptophan

Source

Identifiers

PMID: 22402594
DOI: 10.1007/s00726-012-1250-x

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression, purification and antimicrobial activity of puroindoline A protein and its mutants.PMID 22402594Read ↗

Molecular characterization of the puroindoline-a and b alleles in synthetic hexaploid wheats and in silico functional and structural insights into Pina-D1.Semantic proximity Read ↗

Production of bioactive wheat puroindoline proteins in Nicotiana benthamiana using a virus-based transient expression system.Semantic proximity Read ↗

p-Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation.Semantic proximity Read ↗

Puroindoline-b mutations control the lipid binding interactions in mixed puroindoline-a:puroindoline-b systems.Semantic proximity Read ↗

In planta mutagenesis determines the functional regions of the wheat puroindoline proteins.Semantic proximity Read ↗

Characterization of recombinant pumpkin 2S albumin and mutation studies to unravel potential DNA/RNA binding site.Semantic proximity Read ↗

Antimicrobial activity of the recombinant peptide Melittin-Thanatin with three glycine to tryptophan mutations.Semantic proximity Read ↗

Functional identification of the prnABCD operon and its regulation in Serratia plymuthica.Semantic proximity Read ↗

Snakins: Antimicrobial potential and prospects of genetic engineering for enhanced disease resistance in plantsSemantic proximity Read ↗

Optimization of the wheat puroindoline-a production in Pichia pastorisSemantic proximity Read ↗

Molecular and biochemical characterization of puroindoline a and b alleles in Chinese landraces and historical cultivars.Semantic proximity Read ↗

Structure of RNA-interacting cyclophilin A-like protein from Piriformospora indica that provides salinity-stress tolerance in plants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.