Article
Functional identification of the prnABCD operon and its regulation in Serratia plymuthica.
Applied microbiology and biotechnology - 1 Apr 2018
Liu Xiaoguang, Yu Xiaoli, Yang Yang, Heeb Stephan, Gao Shao, Chan Kok Gan, Cámara Miguel, Gao Kexiang
Abstract excerpt
The antibiotic pyrrolnitrin (PRN) is a tryptophan-derived secondary metabolite that plays an important role in the biocontrol of plant diseases due to its broad-spectrum of antimicrobial activities. The PRN biosynthetic gene cluster remains to be characterised in Serratia plymuthica, though it is highly conserved in PRN-producing bacteria. To better understand PRN biosynthesis and its regulation in Serratia, the...
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