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Article

The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2012

Shi Zhen, Ruvkun Gary

Abstract excerpt

The mevalonate pathway is highly conserved and mediates the production of isoprenoids, which feed into biosynthetic pathways for sterols, dolichol, ubiquinone, heme, isopentenyl adenine, and prenylated proteins. We found that in Caenorhabditis elegans, the nonsterol biosynthetic outputs of the me...

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Identifiers

PMID: 22396595
DOI: 10.1073/pnas.1202421109
PMCID: PMC3311396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22396595-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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