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Article

Fluorescence sensor for the quantification of unbound bilirubin concentrations.

Clinical chemistry - 1 May 2012

Huber Andrew H, Zhu Baolong, Kwan Thomas, Kampf J Patrick, Hegyi Thomas, Kleinfeld Alan M

Abstract excerpt

BACKGROUND: Hyperbilirubinemia in jaundiced neonates is routinely assessed by use of total serum bilirubin. However, the unbound or free form (B(f)), not total bilirubin, crosses the blood-brain barrier and can be neurotoxic. Although the peroxidase-mediated oxidation of bilirubin can be used to measure plasma concentrations of B(f), this measurement is relatively complex and the assay is not routinely used. We...

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Identifiers

PMID: 22395024
DOI: 10.1373/clinchem.2011.176412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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