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Article

Establishment of keratinocyte colonies from small-sized cervical intraepithelial neoplasia specimens.

Journal of cellular physiology - 1 Dec 2012

Bononi Ilaria, Bosi Silvia, Bonaccorsi Gloria, Marci Roberto, Patella Alfredo, Ferretti Stefano, Tognon Mauro, Garutti Paola, Martini Fernanda

Abstract excerpt

The size of human cervical intraepithelial neoplasia (CIN) biopsies is usually very small and standard methods do not allow an adequate number of keratinocytes to be isolated for culturing purposes. In this study, a new approach to establish keratinocyte cultures from small CIN a tissue fragments was developed. Neoplastic specimens and corresponding normal tissues, which were used as controls, were digested with...

Topics

Alphapapillomavirus
Biomarkers
Cell Culture Techniques
Cell Line, Tumor
Cloning, Molecular
Female
Fluorescent Antibody Technique
Genotype
Humans
Keratinocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms, Glandular and Epithelial

Rhodamines

Staining and Labeling

Uterine Cervical Neoplasms

Virus Diseases

Source

Identifiers

PMID: 22392909
DOI: 10.1002/jcp.24088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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