Article
Large expansion of morphologically heterogeneous mammary epithelial cells, including the luminal phenotype, from human breast tumours.
Breast cancer research and treatment - 1 Feb 2002
Krásná L, Dudorkinová D, Vedralová J, Veselý P, Pokorná E, Kudlácková I, Chaloupková A, Petruzelka L, Danes J, Matousková E
Abstract excerpt
Regular expansion of heterogeneous populations of epithelial cells, including the luminal phenotype, was achieved from small biopsies of human breast tumours and cutaneous metastases by optimized feeder layer technique based on irradiated NIH 3T3 cells. Forty-one out of 47 primary tumour specimens and all three cutaneous metastases grew successfully for two to 10 passages in vitro. The main phenotypes of cultured...
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