Article
Targeting persisters for tuberculosis control.
Antimicrobial agents and chemotherapy - 1 May 2012
Zhang Ying, Yew Wing Wai, Barer Michael R
Abstract excerpt
Mycobacterial persisters, the survivors from antibiotic exposure, necessitate the lengthy treatment of tuberculosis (TB) and pose a significant challenge for our control of the disease. We suggest that persisters in TB are heterogeneous in nature and comprise various proportions of the population depending on the circumstances; the mechanisms of their formation are complex and may be related to those required for...
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