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Article

Identification of hot and cold spots in genome of Mycobacterium tuberculosis using Shewhart Control Charts.

Scientific reports - 1 Jan 2012

Das Sarbashis, Duggal Priyanka, Roy Rahul, Myneedu Vithal P, Behera Digamber, Prasad Hanumanthappa K, Bhattacharya Alok

Abstract excerpt

The organization of genomic sequences is dynamic and undergoes change during the process of evolution. Many of the variations arise spontaneously and the observed genomic changes can either be distributed uniformly throughout the genome or be preferentially localized to some regions (hot spots) compared to others. Conversely cold spots may tend to accumulate very few variations or none at all. In order to...

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Identifiers

PMID: 22389766
DOI: 10.1038/srep00297
PMCID: PMC3291883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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