Article
Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population.
Neuroscience letters - 4 Apr 2012
Kaarniranta Kai, Paananen Jussi, Nevalainen Tanja, Sorri Iiris, Seitsonen Sanna, Immonen Ilkka, Salminen Antero, Pulkkinen Leena, Uusitupa Matti
Abstract excerpt
Adiponectin is an adipocyte-expressed protein that regulates the glucose, lipid, and energy metabolism via adiponectin receptors 1 and 2. Obesity is a known risk factor for age-related macular degeneration (AMD). We, therefore, examined associations of single nucleotide polymorphisms in Adiponectin (ADIPOQ) and Adiponectin receptors 1 and 2 (ADIPOR1 and ADIPOR2) genes with the prevalence of advanced AMD in...
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