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Article

Impact of RECK gene polymorphisms and environmental factors on oral cancer susceptibility and clinicopathologic characteristics in Taiwan.

Carcinogenesis - 1 Jul 2011

Chung Tsung-Te, Pan Min-Shing, Kuo Chien-Long, Wong Ruey-Hong, Lin Chiao-Wen, Chen Mu-Kuan, Yang Shun-Fa

Abstract excerpt

Oral cancer is the fourth common male cancer and causally associated with environmental carcinogens in Taiwan. The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) has a significant effect on tumorigenesis by limiting angiogenesis and invasion of tumors through the extracellular matrix. RECK downregulation has been confirmed in many human cancers and associated with lymph node metastasis...

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Identifiers

PMID: 21565829
DOI: 10.1093/carcin/bgr083

Genes

RECK

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