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Article

Apolipoprotein E gene polymorphisms are strong predictors of inflammation and dyslipidemia in rheumatoid arthritis.

The Journal of rheumatology - 1 Feb 2012

Toms Tracey E, Smith Jacqueline P, Panoulas Vasileios F, Blackmore Heather, Douglas Karen M J, Kitas George D

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA), a condition with a strong genetic etiology, is associated with excess cardiovascular disease (CVD). Dyslipidemia in RA may be driven by inflammation and genetic factors. Apolipoprotein E (ApoE) is important for the regulation of lipid levels and CVD risk and immune function in the general population. We compared the frequency of 2 ApoE single-nucleotide polymorphisms (SNP) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22174202
DOI: 10.3899/jrheum.110683

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