Article
Endothelial dysfunction in rheumatoid arthritis: influence of HLA-DRB1 alleles.
Autoimmunity reviews - 1 Jun 2004
Gonzalez-Gay Miguel A, Gonzalez-Juanatey Carlos, Ollier William E
Abstract excerpt
Cardiovascular disease is the commonest cause of premature mortality in rheumatoid arthritis (RA) patients. Vascular endothelial injury is the primary event in atherosclerosis. It has been associated with endothelial dysfunction. We have recently observed that actively treated RA patients had endothelial dysfunction. HLA-DRB1 shared epitope alleles, in particular HLA-DRB1*0404, seem to be implicated in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
