Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tight junctions and differentiation – a chicken or the egg question?

15 Dec 2011

Abstract excerpt

Skin barrier function is indispensable to prevent the uncontrolled loss of water and solutes and to protect the body from external assaults. To fulfil this function, keratinocytes undergo a complex pathway of differentiation that terminates in the formation of the stratum corneum. Additionally, tight junctions (TJs), which are cell-cell junctions localized in the stratum granulosum, are involved in the barrier...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Barrier Structure and Function Studies
Share to Connexins and lens biology
Share to Dermatology and Skin Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22379962
DOI: 10.1111/j.1600-0625.2011.01431.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tight junctions and differentiation – a chicken or the egg question?PMID 22379962Read ↗

Epidermal tight junctions in health and diseaseSemantic proximity Read ↗

Barrier Integrity and Immunity: Exploring the Cutaneous Front Line in Health and DiseaseSemantic proximity Read ↗

Potential Role of the Epidermal Differentiation Complex in the Pathogenesis of PsoriasisSemantic proximity Read ↗

Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders.Semantic proximity Read ↗

Junctions and Inflammation in the SkinSemantic proximity Read ↗

Impaired tight junctions obstruct stratum corneum formation by altering polar lipid and profilaggrin processingSemantic proximity Read ↗

The stratum corneum barrier: impaired function in relation to associated lipids and proteinsSemantic proximity Read ↗

Interactions among stratum corneum defensive functionsSemantic proximity Read ↗

Epidermal differentiation: the bare essentials.Semantic proximity Read ↗

Epidermal Differentiation in Barrier Maintenance and Wound HealingSemantic proximity Read ↗

Endocannabinoid signaling and epidermal differentiationSemantic proximity Read ↗

Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.