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Article

Epidermal tight junctions in health and disease

11 Nov 2014

Abstract excerpt

The skin, the largest organ of the body, is an essential barrier that under homeostatic conditions efficiently protects and/or minimizes damage from both environmental (e.g. microorganisms, physical trauma, ultraviolet radiation) and endogenous (e.g., cancers, inflammation) factors. This formidable barrier function resides mainly in the epidermis, a dynamic, highly-stratified epithelium. The epidermis has 2 major...

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PMID: 25838981
DOI: 10.4161/21688370.2014.974451

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