Article
Barrier Integrity and Immunity: Exploring the Cutaneous Front Line in Health and Disease
25 Apr 2025
Abstract excerpt
Immune responses are influenced by not only immune cells but also the tissue microenvironment where these cells reside. Recent advancements in understanding the underlying molecular mechanisms and structures of the epidermal tight junctions (TJs) and stratum corneum (SC) have significantly enhanced our knowledge of skin barrier functions. TJs, located in the granular layer of the epidermis, are crucial boundary...
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