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Junctions and Inflammation in the Skin

1 May 2014

Abstract excerpt

The skin forms a life-sustaining barrier between the organism and physical environment. The physical barrier of skin is mainly localized in the stratum corneum (SC); however, nucleated epidermis also contributes to the barrier through tight, gap, and adherens junctions (AJs), as well as through desmosomes and cytoskeletal elements. Many inflammatory diseases, such as atopic dermatitis (AD) and psoriasis, are...

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Identifiers

PMID: 24787376
DOI: 10.3109/15419061.2014.905930

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