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Article

Association of genetic polymorphisms in the RET-protooncogene and NRG1 with Hirschsprung disease in Thai patients.

Journal of human genetics - 1 May 2012

Phusantisampan Theerawut, Sangkhathat Surasak, Phongdara Amornrat, Chiengkriwate Piyawan, Patrapinyokul Sakda, Mahasirimongkol Surakameth

Abstract excerpt

Hirschsprung disease (HSCR) is a congenital developmental defect of the enteric nervous system known to be associated with the RET-protooncogene and other candidates. Recently, a genome-wide association study has added NRG1, a regulator of the development of the enteric ganglia precursors, as a n...

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Source

Identifiers

PMID: 22377709
DOI: 10.1038/jhg.2012.18

Genes

NRG1
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22377709-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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