Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population.

Journal of cellular and molecular medicine - 1 Apr 2018

Zhang Yan, Xie Xiaoli, Zeng Jixiao, Wu Qiang, Zhang Ruizhong, Zhu Deli, Xia Huimin

Abstract excerpt

Hirschsprung disease (HSCR) is a genetic disorder characterized by the absence of enteric ganglia. There are more than 15 genes identified as contributed to HSCR by family-based or population-based approaches. However, these findings were not fulfilled to explain the heritability of most sporadic cases. In this study, using 1470 HSCR and 1473 control subjects in South Chinese population, we replicated two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colon
Share to Cytoskeletal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Intergenic

Share to Epistasis, Genetic

Share to Hirschsprung Disease

Share to Multifactor Dimensionality Reduction

Share to Neuregulin-1

Share to Organ Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 29377512
DOI: 10.1111/jcmm.13498
PMCID: PMC5867083

Genes

AUTS2
NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population.PMID 29377512Read ↗

Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease.Semantic proximity Read ↗

A genome-wide association study identifies potential susceptibility loci for Hirschsprung disease.Semantic proximity Read ↗

Effects of NRG1 Polymorphisms on Hirschsprung's Disease Susceptibility: A Meta-analysis.Semantic proximity Read ↗

Mutations in the NRG1 gene are associated with Hirschsprung disease.Semantic proximity Read ↗

Cumulative Risk Impact of RET, SEMA3, and NRG1 Polymorphisms Associated With Hirschsprung Disease in Han Chinese.Semantic proximity Read ↗

Comprehensive analysis of NRG1 common and rare variants in Hirschsprung patients.Semantic proximity Read ↗

Exome sequencing identified NRG3 as a novel susceptible gene of Hirschsprung's disease in a Chinese population.Semantic proximity Read ↗

Fine mapping of the NRG1 Hirschsprung's disease locus.Semantic proximity Read ↗

NRG1 variant effects in patients with Hirschsprung disease.Semantic proximity Read ↗

Contribution of Common Variants in GABRG2, RELN and NRG3 and Interaction Networks to the Risk of Hirschsprung Disease.Semantic proximity Read ↗

The Emerging Genetic Landscape of Hirschsprung Disease and Its Potential Clinical ApplicationsSemantic proximity Read ↗

Significant Association of rs2147555 Genetic Polymorphism in the EDNRB Gene with Hirschsprung Disease in Southern Chinese Children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.