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Article

Advances in molecular genetics of Hirschsprung's disease.

Anatomical record (Hoboken, N.J. : 2007) - 1 Oct 2012

Pan Zhi-Wen, Li Ji-Cheng

Abstract excerpt

Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system, which occurs due to the failure of neural crest cells to fully colonize the gut during embryonic development. It is characterized by the absence of the enteric ganglia in a variable length of the intestine. Substantial progress has been made in understanding the genetic basis of HSCR with the help of advanced genetic analysis...

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PMID: 22815266
DOI: 10.1002/ar.22538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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