Article
Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Mar 2012
Epstein Tolly G, LeMasters Grace K, Bernstein David I, Ericksen Mark B, Martin Lisa J, Ryan Patrick H, Biagini Myers Jocelyn M, Butsch Kovacic Melinda S, Lindsey Mark A, He Hua, Reponen Tiina, Villareal Manuel S, Lockey James E, Bernstein Cheryl K, Khurana Hershey Gurjit K
Abstract excerpt
BACKGROUND: Small proline rich protein 2B (SPRR2B) is a skin and lung epithelial protein associated with allergic inflammation in mice that has not been evaluated in human atopic diseases. OBJECTIVE: To determine whether single-nucleotide polymorphisms (SNPs) in SPRR2B are associated with childhood eczema and with the phenotype of childhood eczema combined with asthma. METHODS: Genotyping for SPRR2B and filaggrin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.