Article
A synonymous variation in protease-activated receptor-2 is associated with atopy in Korean children.
The Journal of allergy and clinical immunology - 1 Dec 2011
Lee Ji Hyun, Kim Kyung Won, Gee Heon Yung, Lee Jaechun, Lee Keun-Hwa, Park Hae-Sim, Kim Seung-Hyun, Kim So Won, Kim Mi Na, Kim Kyu-Earn, Kim Kyung Hwan, Lee Min Goo, Sohn Myung Hyun
Abstract excerpt
BACKGROUND: Atopic diseases are the most common chronic diseases of childhood, and the genetics of atopy are complex and heterogeneous. Protease-activated receptor-2 (PAR-2) is involved in various inflammatory diseases, but the association of PAR-2 with allergic diseases remains unclear. OBJECTIVE: To examine the contribution of genetic variation of PAR-2 to atopic phenotypes in the Korean childhood cohort....
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