Article
Genetic polymorphisms of angiotensinogen and essential hypertension in a Tibetan population.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Nov 2007
Niu Wenquan, Qi Yue, Cen Weijun, Cui Chaoying, Zhuoma Ciren, Cai Dan, Zhou Wenyu, Qiu Changchun
Abstract excerpt
The human angiotensinogen gene (AGT) is a promising candidate for an essential hypertension-susceptibility gene. We aimed to explore the single-locus, haplotype and epistasis patterns of three polymorphisms of AGT (A-20C, A-6G and M235T) and their relation to the risk of essential hypertension in a Tibetan population. The three polymorphisms were genotyped in 333 essential hypertension patients and 235 healthy...
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