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Article

The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.

Bioorganic & medicinal chemistry - 1 Apr 2012

Santner Tobias, Siegmund Vanessa, Marx Andreas, Micura Ronald

Abstract excerpt

Modified nucleoside triphosphates (NTPs) represent powerful building blocks to generate nucleic acids with novel properties by enzymatic synthesis. We have recently demonstrated the access to 2'-SeCH(3)-uridine and 2'-SeCH(3)-cytidine derivatized RNAs for applications in RNA crystallography, using the corresponding nucleoside triphosphates and distinct mutants of T7 RNA polymerase. In the present note, we...

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Identifiers

PMID: 22364745
DOI: 10.1016/j.bmc.2012.01.044
PMCID: PMC3334826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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