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Article

Detection of putative autoantibodies in systemic lupus erythematous using a novel native-conformation protein microarray platform

17 Sept 2020

Abstract excerpt

Objective Conventional immunoassays detect autoantibodies related to systemic lupus erythematosus (SLE) via recognition of epitopes on autoantigens expressed in their denatured rather than native conformational state, casting difficulty in evaluating the genuine pathogenicity of the autoantibodies. We aimed to use a novel high-throughput protein microarray platform to identify autoantibodies against native...

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Share to Advanced Biosensing Techniques and Applications
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PMID: 32941107
DOI: 10.1177/0961203320959696

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