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Disease Tolerance as a Defense Strategy

23 Feb 2012

Abstract excerpt

The immune system protects from infections primarily by detecting and eliminating the invading pathogens; however, the host organism can also protect itself from infectious diseases by reducing the negative impact of infections on host fitness. This ability to tolerate a pathogen's presence is a distinct host defense strategy, which has been largely overlooked in animal and human studies. Introduction of the...

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PMID: 22363001
DOI: 10.1126/science.1214935

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