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Article

Phospholipase C-mediated suppression of dark noise enables single-photon detection in Drosophila photoreceptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Feb 2012

Katz Ben, Minke Baruch

Abstract excerpt

Drosophila photoreceptor cells use the ubiquitous G-protein-mediated phospholipase C (PLC) cascade to achieve ultimate single-photon sensitivity. This is manifested in the single-photon responses (quantum bumps). In photoreceptor cells, dark activation of G(q)α molecules occurs spontaneously and produces unitary dark events (dark bumps). A high rate of spontaneous G(q)α activation and dark bump production...

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Identifiers

PMID: 22357856
DOI: 10.1523/JNEUROSCI.5221-11.2012
PMCID: PMC3319679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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