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Article

Common mechanisms regulating dark noise and quantum bump amplification in Drosophila photoreceptors.

Journal of neurophysiology - 1 Apr 2013

Chu Brian, Liu Che-Hsiung, Sengupta Sukanya, Gupta Amit, Raghu Padinjat, Hardie Roger C

Abstract excerpt

Absolute visual thresholds are limited by "dark noise," which in Drosophila photoreceptors is dominated by brief (∼10 ms), small (∼2 pA) inward current events, occurring at ∼2/s, believed to reflect spontaneous G protein activations. These dark events were increased in rate and amplitude by a point mutation in myosin III (NINAC), which disrupts its interaction with the scaffolding protein, INAD. This phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23365183
DOI: 10.1152/jn.00001.2013
PMCID: PMC3628032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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