Possible suppression of fetal erythropoiesis by the Kell blood group antibody anti-Kp(a).

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Article

Possible suppression of fetal erythropoiesis by the Kell blood group antibody anti-Kp(a).

Immunohematology - 1 Jan 2011

Tuson M, Hue-Roye K, Koval K, Imlay S, Desai R, Garg G, Kazem E, Stockman D, Hamilton J, Reid M E

Abstract excerpt

Antibodies to antigens in the Kell blood group system are usually immunoglobulin G, and, notoriously, anti-K, anti-k, and anti-Kp(a) can cause severe hemolytic transfusion reactions, as well as severe hemolytic disease of the fetus and newborn (HDFN). It has been shown that the titer of anti-K does not correlate with the severity of HDFN because, in addition to immune destruction of red blood cells (RBCs), anti-K...

Topics

Adult
Antibodies
Blood Group Incompatibility
Blood Grouping and Crossmatching
Cytotoxicity, Immunologic
Erythroblastosis, Fetal
Erythrocytes
Erythropoiesis
Female
Fetal Development
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Infant

Infant, Newborn

Kell Blood-Group System

Male

Phenotype

Twins, Dizygotic

Source

Open in PubMed

Identifiers

PMID: 22356520

Genes

Provenance

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