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Article

Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians.

PloS one - 1 Jan 2012

Prasad Pushplata, Kumar Ashok, Gupta Rajiva, Juyal Ramesh C, Thelma B K

Abstract excerpt

Genome-wide association studies and meta-analysis indicate that several genes/loci are consistently associated with rheumatoid arthritis (RA) in European and Asian populations. To evaluate the transferability status of these findings to an ethnically diverse north Indian population, we performed a replication analysis. We investigated the association of 47 single-nucleotide polymorphisms (SNPs) at 43 of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22355377
DOI: 10.1371/journal.pone.0031584
PMCID: PMC3280307

Genes

PTPN22
AFF3
BLK
CCL21
CCR6
CTLA4
PADI4
PTPRC
PXK
TAGAP
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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