Article
In gastroesophageal reflux disease, differential gene expression in the duodenum points towards enhanced chylomicron production and secretion.
Digestive diseases and sciences - 1 Jun 2012
de Vries Durk R, ter Linde José J M, van Boxel Ofke S, van Herwaarden Margot A, Shephard Pierre, Geng Michael M, Schwartz Matthijs P, Samsom Melvin
Abstract excerpt
BACKGROUND: Duodenal signaling affects esophageal motility and perception, both pathophysiological factors in gastroesophageal reflux disease (GERD). Duodenal gene expression abnormalities, contributing to altered esophageal sensorimotor function, have not been reported to date. AIM: To identify differentially expressed genes in GERD patients' duodenum. METHODS: Twenty GERD patients (total 24-h acid exposure...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.