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Brain-Gut Axis Mechanism of Psychological Stress-Exacerbated Acid Reflux Esophageal Injury: A Multi-Omics Study Based on the PPAR Signaling Pathway and Lipid Metabolism

2026-07-27

Abstract excerpt

<title>Abstract</title> <p>Background Psychological stress significantly contributes to refractory gastroesophageal reflux disease, yet the underlying molecular mechanisms remain poorly understood. This study sought to explore the brain-gut axis mechanism through which psychological stress aggravates esophageal injury in a rat model of acid reflux, employing an integrated multi-omics analysis. Methods To achiev...

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Literature Corpus work
6353b401-0489-51e6-b60d-85084e3dfa1f
DOI
10.21203/rs.3.rs-10276668/v1
Open publication

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Brain-Gut Axis Mechanism of Psychological Stress-Exacerbated Acid Reflux Esophageal Injury: A Multi-Omics Study Based on the PPAR Signaling Pathway and Lipid MetabolismDOI 10.21203/rs.3.rs-10276668/v1
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