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Article

Systematic detection of epistatic interactions based on allele pair frequencies.

PLoS genetics - 1 Feb 2012

Ackermann Marit, Beyer Andreas

Abstract excerpt

Epistatic genetic interactions are key for understanding the genetic contribution to complex traits. Epistasis is always defined with respect to some trait such as growth rate or fitness. Whereas most existing epistasis screens explicitly test for a trait, it is also possible to implicitly test for fitness traits by searching for the over- or under-representation of allele pairs in a given population. Such...

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Identifiers

PMID: 22346757
DOI: 10.1371/journal.pgen.1002463
PMCID: PMC3276547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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