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Methionine restriction for cancer therapy: A comprehensive review of mechanisms and clinical applications

6 Jan 2025

Abstract excerpt

Methionine restriction (MR) has shown significant promise in cancer therapy because it targets the unique methionine dependency of many tumors. However, despite extensive research on MR, a clear synthesis of preclinical findings and their translation into clinical settings is lacking. This review aims to address this gap by consolidating existing evidence, identifying challenges, and highlighting opportunities...

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PMID: 41550357
DOI: 10.1016/j.cpt.2025.01.002

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