Article
Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Jun 1990
Schiestl R H, Gietz R D, Hastings P J, Wintersberger U
Abstract excerpt
The frequency of intra- and interchromosomal recombination was determined in RAD18 and rad18 deletion and rad18-3 mutant strains. It was found that spontaneous interchromosomal recombination at trp5, his1, ade2, and MAT was elevated 10- to 70-fold in the rad18-3 and rad18 delta mutants as compared to the RAD+ strains. On the other hand the frequencies of spontaneous intrachromosomal recombination for the his3...
Topics
- Chromosomes, Fungal
- DNA Repair
- Diploidy
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genotype
- Mutation
- Recombination, Genetic
- Saccharomyces cerevisiae
- Sister Chromatid Exchange
- Ultraviolet Rays
