Genetic evidence for different RAD52-dependent intrachromosomal recombination pathways in Saccharomyces cerevisiae.

Abstract excerpt

Mutations in the RecA-like genes RAD51 and RAD57 reduce the frequency of gene conversion/reciprocal exchange between inverted repeats 7-fold. However, they enhance the frequency of deletions between direct repeats 5-12-fold. These induced deletions are RAD1- and RAD52-dependent. On the basis of these results it is proposed that there are several RAD52-dependent pathways of recombination: the recombinational...

Topics

• Adenosine Triphosphatases
• Chromosomes, Fungal
• DNA Repair Enzymes
• DNA-Binding Proteins
• Diploidy
• Endonucleases
• Fungal Proteins
• Gene Conversion
• Gene Deletion
• Meiosis
• Mitosis
• Mutation