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Article

MicroRNAs and cataracts: correlation among let-7 expression, age and the severity of lens opacity

14 Feb 2012

Abstract excerpt

BACKGROUND: Let-7 microRNA is an important regulator of cellular ageing and tissue senescence. The objective of this study is to evaluate the expression of let-7a/let-7b/let-7c microRNAs in human age-related cataracts. AIM: To evaluate the correlation among the severity of lens opacity, the level of let-7a/let-7b/let-7c microRNA expression and patient age in the context of age-related cataracts. METHODS: The...

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PMID: 22334139
DOI: 10.1136/bjophthalmol-2011-300585

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