Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis

14 Aug 2017

Abstract excerpt

BACKGROUND: Age-related cataracts are related to oxidative stress. However, the genome-wide screening of cataract related oxidative stress related genes are not thoroughly investigated. Our study aims to identify cataract regulated miRNA target genes that are related to oxidative stress and to propose a new possible mechanism for cataract formation. METHODS: Microarrays were used to determine the mRNA expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexins and lens biology
Share to Intraocular Surgery and Lenses
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28806956
DOI: 10.1186/s12886-017-0537-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesisPMID 28806956Read ↗

lncRNA: a promising target for cataractsSemantic proximity Read ↗

Identification of tRNA-derived small RNAs expression profiles and their potential functions in age-related cataractSemantic proximity Read ↗

Identification of H2O2 induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataractSemantic proximity Read ↗

miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis NetworksSemantic proximity Read ↗

Differentially expressed gene profiles and associated ceRNA network in ATG7-Deficient lens epithelial cells under oxidative stressSemantic proximity Read ↗

RNA sequencing and bioinformatics analysis of human lens epithelial cells in age-related cataractSemantic proximity Read ↗

Transcriptome sequencing and microRNA–mRNA regulatory network construction in the lens from a Na 2 Se0 3 -induced Sprague Dawley rat cataract modelSemantic proximity Read ↗

Cataract Review of Integrating Pathogenic Mechanisms, Experimental Models, and Therapeutic DevelopmentSemantic proximity Read ↗

Nuclear and Mitochondrial DNA of Age-Related Cataract Patients Are Susceptible to Oxidative DamageSemantic proximity Read ↗

LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 ExpressionSemantic proximity Read ↗

Panel-based targeted exome sequencing reveals novel candidate susceptibility loci for age-related cataracts in Chinese Cohort.Semantic proximity Read ↗

Discrepant Expression of MicroRNAs in Transparent and Cataractous Human LensesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.