Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A functional variant in the promoter region regulates the C-reactive protein gene and is a potential candidate for increased risk of atrial fibrillation.

Journal of internal medicine - 1 Sept 2012

Chang S-N, Tsai C-T, Wu C-K, Lee J-K, Lai L-P, Huang S-W, Huang L-Y, Tseng C-D, Lin J-L, Chiang F-T, Hwang J-J

Abstract excerpt

OBJECTIVES: In a large population-based cohort, the level of C-reactive protein (CRP) in patients at baseline predicts an increased risk of future development of atrial fibrillation (AF). The mechanism of this increased risk is unknown. Furthermore, both the molecular effects of CRP on atrial myo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Fibrillation
Share to C-Reactive Protein
Share to Calcium Channels, L-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Heart Atria

Share to Linkage Disequilibrium

Share to Myocytes, Cardiac

Share to Risk Assessment

Source

Identifiers

PMID: 22329434
DOI: 10.1111/j.1365-2796.2012.02531.x

Genes

CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22329434-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional variant in the promoter region regulates the C-reactive protein gene and is a potential candidate for increased risk of atrial fibrillation.PMID 22329434Read ↗

C-reactive protein gene polymorphism predicts the risk of thromboembolic stroke in patients with atrial fibrillation: a more than 10-year prospective follow-up study.Semantic proximity Read ↗

Does elevated C-reactive protein increase atrial fibrillation risk? A Mendelian randomization of 47,000 individuals from the general population.Semantic proximity Read ↗

Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation.Semantic proximity Read ↗

A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein.Semantic proximity Read ↗

Human CRP Gene Polymorphism Influences CRP LevelsSemantic proximity Read ↗

Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level.Semantic proximity Read ↗

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels.Semantic proximity Read ↗

Genetic determinants of C-reactive protein.Semantic proximity Read ↗

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.Semantic proximity Read ↗

Ceruloplasmin and atrial fibrillation: evidence of causality from a population-based Mendelian randomization study.Semantic proximity Read ↗

C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.Semantic proximity Read ↗

CRP gene variation and risk of community-acquired pneumonia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.