Article
BMD values and GSTM3 gene polymorphisms in combination with GSTT1/GSTM1 genes: a genetic association study in Slovenian elderly.
Gerontology - 1 Jan 2012
Jurkovic Mlakar Simona, Prezelj Janez, Osredkar Josko, Marc Janja
Abstract excerpt
BACKGROUND: Much research suggests that oxidative stress is associated with osteoporosis development. Glutathione S-transferases mu3 (GSTM3) are an important group of detoxifying enzymes that eliminate oxidative stress-related products. OBJECTIVES: To examine the associations of functional GSTM3 gene polymorphisms (Val224Ile and insdelAGG), their haplotypes and, in combination with GSTT1-null and GSTM1-null...
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