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Article

Clinical Escherichia coli isolates utilize alpha-hemolysin to inhibit in vitro epithelial cytokine production.

Microbes and infection - 1 Jul 2012

Hilbert David W, Paulish-Miller Teresa E, Tan Chee K, Carey Alison J, Ulett Glen C, Mordechai Eli, Adelson Martin E, Gygax Scott E, Trama Jason P

Abstract excerpt

Uropathogenic Escherichia coli is the primary cause of urinary tract infections, which affects over 60% of women during their lifetime. UPEC exhibits a number of virulence traits that facilitate colonization of the bladder, including inhibition of cytokine production by bladder epithelial cells. The goal of this study was to identify the mechanism of this inhibition. We observed that cytokine suppression was...

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Identifiers

PMID: 22326301
DOI: 10.1016/j.micinf.2012.01.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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