Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HBL-1 patterns synaptic remodeling in C. elegans.

Neuron - 9 Feb 2012

Thompson-Peer Katherine L, Bai Jihong, Hu Zhitao, Kaplan Joshua M

Abstract excerpt

During development, circuits are refined by the dynamic addition and removal of synapses; however, little is known about the molecular mechanisms that dictate where and when synaptic refinement occurs. Here we describe transcriptional mechanisms that pattern remodeling of C. elegans neuromuscular junctions (NMJs). The embryonic GABAergic DD motor neurons remodel their synapses, whereas the later born VD neurons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Body Patterning
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to gamma-Aminobutyric Acid

Share to Motor Neurons

Share to Neuromuscular Junction

Share to Receptors, Cytoplasmic and Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 22325199
DOI: 10.1016/j.neuron.2011.11.025
PMCID: PMC3278716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HBL-1 patterns synaptic remodeling in C. elegans.PMID 22325199Read ↗

A transcriptional program promotes remodeling of GABAergic synapses in Caenorhabditis elegans.Semantic proximity Read ↗

Spatiotemporal control of a novel synaptic organizer molecule.Semantic proximity Read ↗

Building stereotypic connectivity: mechanistic insights into structural plasticity from C. elegans.Semantic proximity Read ↗

Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling.Semantic proximity Read ↗

Changing synaptic specificities in the nervous system of Caenorhabditis elegans: differentiation of the DD motoneurons.Semantic proximity Read ↗

A molecular atlas of adult <i>C. elegans</i> motor neurons reveals ancient diversity delineated by conserved transcription factor codesSemantic proximity Read ↗

C. elegans ZAG-1, a Zn-finger-homeodomain protein, regulates axonal development and neuronal differentiation.Semantic proximity Read ↗

Highwire regulates synaptic growth in Drosophila.Semantic proximity Read ↗

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons.Semantic proximity Read ↗

RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.Semantic proximity Read ↗

Regulation of C. elegans neuronal differentiation by the ZEB-family factor ZAG-1 and the NK-2 homeodomain factor CEH-28.Semantic proximity Read ↗

A screen for genes that regulate synaptic growth reveals mechanisms that stabilize synaptic strengthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.