Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A predictive model of treatment outcome in patients with chronic HCV infection using IL28B and PD-1 genotyping.

Journal of hepatology - 1 Jun 2012

Vidal-Castiñeira Jose Ramón, López-Vázquez Antonio, Alonso-Arias Rebeca, Moro-García Marco Antonio, Martinez-Camblor Pablo, Melón Santiago, Prieto Jesús, López-Rodriguez Rosario, Sanz-Cameno Paloma, Rodrigo Luis, Pérez-López Rosa, Pérez-Álvarez Ramón, López-Larrea Carlos

Abstract excerpt

BACKGROUND & AIMS: The advent of new chronic hepatitis C virus (HCV) therapies requires characterization of patients in order to predict adequate treatment. A good candidate marker is Programmed Cell Death-1 (PD-1) which is involved in progression of HCV infection. The aim of this study was to analyse the effect of several single nucleotide polymorphisms of PD-1 gene and several previously associated factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C, Chronic
Share to Interferons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukins

Share to Logistic Models

Share to Polymorphism, Single Nucleotide

Share to Predictive Value of Tests

Share to Programmed Cell Death 1 Receptor

Share to Treatment Outcome

Source

Identifiers

PMID: 22322230
DOI: 10.1016/j.jhep.2012.01.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A predictive model of treatment outcome in patients with chronic HCV infection using IL28B and PD-1 genotyping.PMID 22322230Read ↗

IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study.Semantic proximity Read ↗

Predicting response to therapy in chronic hepatitis C: an approach combining interleukin-28B gene polymorphisms and clinical data.Semantic proximity Read ↗

Novel findings for the development of drug therapy for various liver diseases: Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C.Semantic proximity Read ↗

Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C.Semantic proximity Read ↗

Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors.Semantic proximity Read ↗

Variations at multiple genes improve interleukin 28B genotype predictive capacity for response to therapy against hepatitis C infection.Semantic proximity Read ↗

Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection.Semantic proximity Read ↗

Interleukin-28B gene non-TT allele strongly predicts treatment failure for genotype 1 infected chronic hepatitis C patients with advanced fibrosis: a case control study.Semantic proximity Read ↗

Variation in both IL28B and KIR2DS3 genes influence pegylated interferon and ribavirin hepatitis C treatment outcome in HIV-1 co-infection.Semantic proximity Read ↗

Genetic variations of IL-28B and PD-1 are in association with the susceptibility and outcomes of HCV infection in Southeast China.Semantic proximity Read ↗

Impact of IL28 Genotypes and Modeling the Interactions of HCV Core Protein on Treatment of Hepatitis C.Semantic proximity Read ↗

IL28B polymorphism may guide pegylated interferon plus ribavirin therapy even after curative treatment for hepatitis C virus-related hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.