Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Morphogens and hepatic stellate cell fate regulation in chronic liver disease.

Journal of gastroenterology and hepatology - 1 Mar 2012

Tsukamoto Hidekazu, Zhu Nian-Ling, Wang Jiaohong, Asahina Kinji, Machida Keigo

Abstract excerpt

Hepatic stellate cells (HSC) are the liver mesenchymal cell type which responds to hepatocellular damage and participates in wound healing. Although HSC myofibroblastic trans-differentiation (activation) is implicated in excessive extracellular matrix deposition, molecular understanding of this phenotypic switch from the viewpoint of cell fate regulation is limited. Recent studies demonstrate the roles of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipogenesis
Share to Chronic Disease
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatic Stellate Cells

Share to Liver Diseases

Share to Morphogenesis

Share to PPAR gamma

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22320925
DOI: 10.1111/j.1440-1746.2011.07022.x
PMCID: PMC3337168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Morphogens and hepatic stellate cell fate regulation in chronic liver disease.PMID 22320925Read ↗

Epigenetic cell fate regulation of hepatic stellate cellsSemantic proximity Read ↗

Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.Semantic proximity Read ↗

Hedgehog signaling in cholangiocytes.Semantic proximity Read ↗

Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.Semantic proximity Read ↗

Mesoderm/mesenchyme homeobox l as a potential target that orchestrates hepatic stellate cell activationSemantic proximity Read ↗

Hepatic stellate cells: unique characteristics in cell biology and phenotype.Semantic proximity Read ↗

Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cellsSemantic proximity Read ↗

Control of Hepatic Differentiation by Activin/TGF&beta; SignalingSemantic proximity Read ↗

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3Semantic proximity Read ↗

Fibrogenic signalling in hepatic stellate cells.Semantic proximity Read ↗

[Hepatic stellate cells: it's role in normal and pathological conditions].Semantic proximity Read ↗

Investigating the role of Wnt3a and Wnt5a as critical factors of hepatic stellate cell activation in acute toxicant-induced liver injurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.