Article
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.
Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2012
Grad Yonatan H, Lipsitch Marc, Feldgarden Michael, Arachchi Harindra M, Cerqueira Gustavo C, Fitzgerald Michael, Godfrey Paul, Haas Brian J, Murphy Cheryl I, Russ Carsten, Sykes Sean, Walker Bruce J, Wortman Jennifer R, Young Sarah, Zeng Qiandong, Abouelleil Amr, Bochicchio James, Chauvin Sara, Desmet Timothy, Gujja Sharvari, McCowan Caryn, Montmayeur Anna, Steelman Scott, Frimodt-Møller Jakob, Petersen Andreas M, Struve Carsten, Krogfelt Karen A, Bingen Edouard, Weill François-Xavier, Lander Eric S, Nusbaum Chad, Birren Bruce W, Hung Deborah T, Hanage William P
Abstract excerpt
The degree to which molecular epidemiology reveals information about the sources and transmission patterns of an outbreak depends on the resolution of the technology used and the samples studied. Isolates of Escherichia coli O104:H4 from the outbreak centered in Germany in May-July 2011, and the much smaller outbreak in southwest France in June 2011, were indistinguishable by standard tests. We report a molecular...
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