Article
Using Neisseria meningitidis genomic diversity to inform outbreak strain identification.
PLoS pathogens - 1 May 2021
Retchless Adam C, Chen Alex, Chang How-Yi, Blain Amy E, McNamara Lucy A, Mustapha Mustapha M, Harrison Lee H, Wang Xin
Abstract excerpt
Meningococcal disease is a life-threatening illness caused by the human-restricted bacterium Neisseria meningitidis. Outbreaks in the USA involve at least two cases in an organization or community caused by the same serogroup within three months. Genome comparisons, including phylogenetic analysis and quantification of genome distances can provide confirmatory evidence of pathogen transmission during an outbreak....
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