Article
Public health value of next-generation DNA sequencing of enterohemorrhagic Escherichia coli isolates from an outbreak.
Journal of clinical microbiology - 1 Jan 2013
Underwood Anthony P, Dallman Tim, Thomson Nicholas R, Williams Michaela, Harker Katy, Perry Neil, Adak Bob, Willshaw Geraldine, Cheasty Tom, Green Jonathan, Dougan Gordon, Parkhill Julian, Wain John
Abstract excerpt
In 2009, an outbreak of enterohemorrhagic Escherichia coli (EHEC) on an open farm infected 93 persons, and approximately 22% of these individuals developed hemolytic-uremic syndrome (HUS). Genome sequencing was used to investigate outbreak-derived animal and human EHEC isolates. Phylogeny based on the whole-genome sequence was used to place outbreak isolates in the context of the overall E. coli species and the...
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