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Article

Genetic variations in microRNA genes and susceptibility to hepatocellular carcinoma.

Genetics and molecular research : GMR - 20 Mar 2015

Li D, Peng J J, Tan Y, Chen T, Wei D, Du M, Zhang T

Abstract excerpt

We conducted a hospital-based case-control study to investigate the effect of the miR-146aG>C and miR-499A>G polymorphisms on the risk of hepatocellular carcinoma (HCC) in a Chinese population. This study was 1:1 matched case-control study consisting of 184 HCC patients and 184 control subjects. miR-146aG>C and miR-499A>G polymorphisms were genotyped by polymerase chain reaction-restriction fragment length...

Topics

Alleles
Asian People
Carcinoma, Hepatocellular
Case-Control Studies
China
Female
Genetic Predisposition to Disease
Humans
Liver Neoplasms
Male
MicroRNAs
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Risk Factors

Sequence Analysis, DNA

Source

Identifiers

PMID: 25867338
DOI: 10.4238/2015.March.20.2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25867338-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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